PPARα agonist 2
PPARα agonist 2 (compound 4u) is a potent and selective PPARα agonist with an EC50 of 37 nM. PPARα agonist 2 exhibits >2,700-fold selectivity for PPARα over other PPAR isoforms. PPARα agonist 2 has the potential for retinal disorders research.
For research use only. We do not sell to patients.
- CAS No.: 2376590-40-6
- Formula: C22H20FNO3
- Molecular Weight:365.40
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PPARα 37 nM (EC50) |
Chemical Information
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CAS No. 2376590-40-6
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Appearance Solid
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Molecular Weight 365.40
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Formula C22H20FNO3
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Color White to off-white
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SMILES
O=C(O)C1=CC=CC(NCC2=CC=C(OCC3=CC=C(F)C=C3)C(C)=C2)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMF : 20 mg/mL (54.73 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF | 1 mM | 2.7367 mL | 13.6836 mL | 27.3673 mL | 68.4182 mL |
| 5 mM | 0.5473 mL | 2.7367 mL | 5.4735 mL | 13.6836 mL | |
| 10 mM | 0.2737 mL | 1.3684 mL | 2.7367 mL | 6.8418 mL | |
| 15 mM | 0.1824 mL | 0.9122 mL | 1.8245 mL | 4.5612 mL | |
| 20 mM | 0.1368 mL | 0.6842 mL | 1.3684 mL | 3.4209 mL | |
| 25 mM | 0.1095 mL | 0.5473 mL | 1.0947 mL | 2.7367 mL | |
| 30 mM | 0.0912 mL | 0.4561 mL | 0.9122 mL | 2.2806 mL | |
| 40 mM | 0.0684 mL | 0.3421 mL | 0.6842 mL | 1.7105 mL | |
| 50 mM | 0.0547 mL | 0.2737 mL | 0.5473 mL | 1.3684 mL |
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