288574-78-7
Chemical Structure
Zinpyr-1
- CAS No.: 288574-78-7
- Formula:C46H36Cl2N6O5
- Molecular Weight:823.72
IUPAC Name: 4',5'-bis((bis(pyridin-2-ylmethyl)amino)methyl)-2',7'-dichloro-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
InChIKey: QZKKSPLNXQJQRQ-UHFFFAOYSA-N
SMILES: O=C1OC2(C3=C(OC4=C2C=C(Cl)C(O)=C4CN(CC5=NC=CC=C5)CC6=NC=CC=C6)C(CN(CC7=NC=CC=C7)CC8=NC=CC=C8)=C(O)C(Cl)=C3)C9=C1C=CC=C9
Biological Activity: Zinpyr-1 is a zinc-responsive fluorescent indicator and a membrane-permeable metal-binding probe. Zinpyr-1 forms a complex with Mn2+ ions and generates a fluorescence turn-on signal. Zinpyr-1 binds to free zinc ions in serum, enabling quantitative detection of free zinc concentration. Zinpyr-1 produces fluorescence signals reflecting the relative zinc concentration in plant root cells, localizes to specific layers of plant root cells, and can be used to support analyses related to plant zinc transporter mutations and homeostasis[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Zinpyr-1 | 95.85% | Zinpyr-1 is a zinc-responsive fluorescent indicator and a membrane-permeable metal-binding probe. Zinpyr-1 forms a complex with Mn2+ ions and generates a fluorescence turn-on signal. Zinpyr-1 binds to free zinc ions in serum, enabling quantitative detection of free zinc concentration. Zinpyr-1 produces fluorescence signals reflecting the relative zinc concentration in plant root cells, localizes to specific layers of plant root cells, and can be used to support analyses related to plant zinc transporter mutations and homeostasis. | ||||||||||||||||||||
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- [1]. You Y, et al. Manganese displacement from Zinpyr-1 allows zinc detection by fluorescence microscopy and magnetic resonance imaging. Chem Commun (Camb). 2010;46(23):4139-4141. [Content Brief]
- [2]. Alker W, et al. A Zinpyr-1-based Fluorimetric Microassay for Free Zinc in Human Serum. Int J Mol Sci. 2019;20(16):4006. Published 2019 Aug 16. [Content Brief]
- [3]. Sinclair SA, et al. The use of the zinc-fluorophore, Zinpyr-1, in the study of zinc homeostasis in Arabidopsis roots. New Phytol. 2007;174(1):39-45. [Content Brief]
Keywords
