2891663-21-9
2891663-21-9
Chemical Structure
RORγt inverse agonist 38
- CAS No.: 2891663-21-9
- Formula:C23H15Cl2F4N3O2
- Molecular Weight:512.28
IUPAC Name: 3-(2-chloro-6-fluorophenyl)-5-(1-(3-chlorophenyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)-4-(cyclopropoxymethyl)isoxazole
InChIKey: NRVNUOYPOQZERF-UHFFFAOYSA-N
SMILES: FC1=CC=CC(Cl)=C1C2=NOC(C3=C(C(F)(F)F)N(C4=CC(Cl)=CC=C4)N=C3)=C2COC5CC5
Biological Activity: RORγt inverse agonist 38 (C102) is a RORγt inverse agonist. RORγt inverse agonist 38 can be used for the research of psoriasis, autoimmune thyroiditis, inflammatory bowel disease, cancer, and other conditions[1].
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RORγt inverse agonist 38 | RORγt inverse agonist 38 (C102) is a RORγt inverse agonist. RORγt inverse agonist 38 can be used for the research of psoriasis, autoimmune thyroiditis, inflammatory bowel disease, cancer, and other conditions. | |||||||||||||||||||||
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RORγ/DHODH-IN-1 | RORγ/DHODH-IN-1 (compound 1404), a deuterium labeled compound, is a dual RORγ and DHODH inhibitor with IC50 values of 9.7 nM and 100 nM, repaectively. RORγ/DHODH-IN-1 blocks the replication of SARS-CoV-2, HCMV, and non-enveloped DNA virus (HAdV5). | |||||||||||||||||||||
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References
