2909474-29-7
2909474-29-7
Chemical Structure
E0924G
- CAS No.: 2909474-29-7
- Formula:C12H12N2O3
- Molecular Weight:232.24
InChIKey: SYYTXZNUUAHTTN-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C)O1)NC2=NC=CC(OC)=C2
Biological Activity: E0924G is an orally active activator for PPARδ with EC50 of 2.82 μM. E0924G promotes the upregulation of osteoprotegerin (OPG) with an EC50 of 0.29 μM. E0924G reduces RANKL-induced osteoclast differentiation and inhibites F-actin ring formation in RAW264.7 macrophages. E0924G regulates the bone density and bone loss in ovariectomized (OVX) and age-related osteoporosis models[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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E0924G | 99.17% | E0924G is an orally active activator for PPARδ with EC50 of 2.82 μM. E0924G promotes the upregulation of osteoprotegerin (OPG) with an EC50 of 0.29 μM. E0924G reduces RANKL-induced osteoclast differentiation and inhibites F-actin ring formation in RAW264.7 macrophages. E0924G regulates the bone density and bone loss in ovariectomized (OVX) and age-related osteoporosis models. | ||||||||||||||||||||
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References
Keywords
