2910938-59-7
2910938-59-7
Chemical Structure
CK156
- CAS. Nr.: 2910938-59-7
- Formula:C21H25N5O3
- Molecular Weight:395.45
IUPAC Name: (13Z,14E)-N-(tert-butyl)-3,6-dioxa-9-aza-1(3,5)-pyrazolo[1,5-a]pyrimidina-2(1,3)-benzenacyclononaphane-24-carboxamide
InChIKey: YCFFONJEHNSECY-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C2C=C1OCCOCCNC3=NC4=C2C=NN4C=C3)NC(C)(C)C
Biological Activity: CK156, a chemical probe, is a highly selective death-associated protein kinase (DAPK) inhibitor with IC50s of 182 nM,34 μM, and 39 μM in the DRAK1 NanoBRET assay for DRAK1, CK2a1, and CK2a2, respectively. CK156 can be used for the research of autoimmune and inflammatory diseases[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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CK156 | 99.60% | CK156, a chemical probe, is a highly selective death-associated protein kinase (DAPK) inhibitor with IC50s of 182 nM,34 μM, and 39 μM in the DRAK1 NanoBRET assay for DRAK1, CK2a1, and CK2a2, respectively. CK156 can be used for the research of autoimmune and inflammatory diseases. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.55
HY-133553RET-IN-3 -
Similarity Score 0.52
HY-174214AAK1-IN-8 -
Similarity Score 0.51
HY-151382CK2-IN-3 -
Similarity Score 0.50
HY-136534RET V804M-IN-1 -
Similarity Score 0.50
HY-148742RET-IN-21 -
Similarity Score 0.49
HY-103022RRepotrectinib (Standard) -
Similarity Score 0.48
HY-117626LP-935509 -
Similarity Score 0.47
HY-181780TRK-IN-34 -
Similarity Score 0.46
HY-185545NTRK1-ligand-1 -
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