2922402-01-3
2922402-01-3
Chemical Structure
MPO-IN-10
- CAS 番号: 2922402-01-3
- Formula:C23H25N3O
- Molecular Weight:359.46
InChIKey: WIXBJCBLXQEETC-IWMITWMQSA-N
SMILES: O=C1N(C2=CC=C(C=CN3)C3=C2)C[C@@H](C4=CC=C([C@H]5CCCN5)C=C4)[C@@H]1C
Biological Activity: MPO-IN-10 is an orally active, selective, and irreversible inhibitor of myeloperoxidase (MPO), with an IC50 of 0.080 μM against human MPO. MPO-IN-10 exhibits higher selectivity for extracellular MPO over intracellular (neutrophil) MPO. MPO-IN-10 can be used in the study of inflammatory diseases such as vascular disorders[1].
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MPO-IN-10 | MPO-IN-10 is an orally active, selective, and irreversible inhibitor of myeloperoxidase (MPO), with an IC50 of 0.080 μM against human MPO. MPO-IN-10 exhibits higher selectivity for extracellular MPO over intracellular (neutrophil) MPO. MPO-IN-10 can be used in the study of inflammatory diseases such as vascular disorders. | |||||||||||||||||||||
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References
Keywords
