2976403-41-3
2976403-41-3
Chemical Structure
BRD4 Inhibitor-25
- CAS No.: 2976403-41-3
- Formula:C29H27N5O6S
- Molecular Weight:573.62
IUPAC Name: N-(4-isopropoxyphenyl)-4-(1H-tetrazol-5-yl)benzamide
InChIKey: SUMJFWHWPZJWDQ-UHFFFAOYSA-N
SMILES: [O-][N+]1=C(C(C2=CC=CC=C2)=NO1)COC(COC3=C(C=C(C=C3C)C4=NC5=C(C6=C(S5)CN(CC6)C)C(N4)=O)C)=O
Biological Activity: BRD4 Inhibitor-25 is a BRD4 inhibitor with IC50s of 0.82 μM, 1.94 μM for BD1 and BD2 domains of BRD4. BRD4 Inhibitor-25 induces apoptotic and autophagy cell death in ovarian cancer cells. BRD4 Inhibitor-25 can be used in the research of cancers, cardiovascular, neuromuscular and inflammatory disorders.
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BRD4 Inhibitor-25 | BRD4 Inhibitor-25 is a BRD4 inhibitor with IC50s of 0.82 μM, 1.94 μM for BD1 and BD2 domains of BRD4. BRD4 Inhibitor-25 induces apoptotic and autophagy cell death in ovarian cancer cells. BRD4 Inhibitor-25 can be used in the research of cancers, cardiovascular, neuromuscular and inflammatory disorders. | |||||||||||||||||||||
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