299173-64-1

17-Demethoxy-reblastatin Chemical Structure
299173-64-1

Chemical Structure

17-Demethoxy-reblastatin

Synonym(s): 17-DR

  • CAS No.: 299173-64-1
  • Formula:C28H42N2O7
  • Molecular Weight:518.64

InChIKey: HUXWGTSMSXMDBH-UQMARRQJSA-N

SMILES: C[C@@H](/C=C1C)[C@@H](O)[C@@H](OC)C[C@H](C)CC2=CC(O)=CC(NC(/C(C)=C/CC[C@H](OC)[C@H]\1OC(N)=O)=O)=C2

Biological Activity: 17-Demethoxy-reblastatin (17-DR) is an inhibitor for heat shock protein 90 (Hsp90), with an IC50 of 1.82 μM for yeast Hsp90 ATPase. 17-Demethoxy-reblastatin inhibits the proliferation of cancer cell HepG2 and SMMC7721, reduces the colony formation, and induces apoptosis through mitochondria and caspase mediated pathway[1].

Cat. No. Product Name Purity Description Pricing
HY-164372 		17-Demethoxy-reblastatin 17-Demethoxy-reblastatin (17-DR) is an inhibitor for heat shock protein 90 (Hsp90), with an IC50 of 1.82 μM for yeast Hsp90 ATPase. 17-Demethoxy-reblastatin inhibits the proliferation of cancer cell HepG2 and SMMC7721, reduces the colony formation, and induces apoptosis through mitochondria and caspase mediated pathway.
Pricing 
Expand Hide
loading...
/
  • /
loading...
Size Price
Stock Quantity Availability Operate
/
In-stock
(Estimated to ship on )
(Estimated to ship TODAY)
Estimated to ship on
(Estimated to ship TODAY)

Amount:

USD 0.00

This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

Pricing 
Expand Hide
References

Keywords