3024916-67-1
3024916-67-1
Chemical Structure
MASTL-IN-1
- No. CAS: 3024916-67-1
- Formula:C21H25N9
- Molecular Weight:403.48
InChIKey: MVYWULXPOKYILU-UHFFFAOYSA-N
SMILES: CN1C(C(N=C2N)=CC3=C2C=NC(NC4=NC=CC(C(CC)(N)CC)=C4)=C3)=CN=N1
Biological Activity: MASTL-IN-1 is a selective and orally active MASTL inhibitor with a Ki <0.03 nM. MASTL-IN-1 inhibits phosphorylation of ENSA and inhibits proliferation in cancer cells. MASTL-IN-1 induces tumor growth inhibition and stasis in pancreatic cancer xenograft models[1].
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MASTL-IN-1 | 99.54% | MASTL-IN-1 is a selective and orally active MASTL inhibitor with a Ki <0.03 nM. MASTL-IN-1 inhibits phosphorylation of ENSA and inhibits proliferation in cancer cells. MASTL-IN-1 induces tumor growth inhibition and stasis in pancreatic cancer xenograft models. | ||||||||||||||||||||
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References
Keywords
