3028684-07-0
3028684-07-0
Chemical Structure
D2R/D3R/5-HT1AR agonist 1
- CAS No.: 3028684-07-0
- Formula:C21H35N5O2S
- Molecular Weight:421.60
InChIKey: FVNHYWSEBRKPPN-KRWDZBQOSA-N
SMILES: O=C(N1CCC(CN([C@@H](CC2)CC3=C2N=C(N)S3)CCC)CC1)N4CCOCC4
Biological Activity: D2R/D3R/5-HT1AR agonist 1 (compound 22b) is an orally active triple-target D2R/D3R/5-HT1AR agonist with EC50 values of 1.29, 1.05 and 153.5 nM. D2R/D3R/5-HT1AR agonist 1 can improve the behavioral disorders induced by MPTP (HY-W114750) and exerts anti-depression effect. D2R/D3R/5-HT1AR agonist 1 can be used for the research of Parkinson's disease and depression[1].
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D2R/D3R/5-HT1AR agonist 1 | D2R/D3R/5-HT1AR agonist 1 (compound 22b) is an orally active triple-target D2R/D3R/5-HT1AR agonist with EC50 values of 1.29, 1.05 and 153.5 nM. D2R/D3R/5-HT1AR agonist 1 can improve the behavioral disorders induced by MPTP (HY-W114750) and exerts anti-depression effect. D2R/D3R/5-HT1AR agonist 1 can be used for the research of Parkinson's disease and depression. | |||||||||||||||||||||
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