3032392-65-4

GK718 Chemical Structure
3032392-65-4

Chemical Structure

GK718

  • CAS No.: 3032392-65-4
  • Formula:C26H30Cl2N4O3
  • Molecular Weight:517.45

InChIKey: UFARUDAPUKLDQM-PPLJNSMQSA-N

SMILES: O=C([C@@H]1NCCC1)NCC2=CC=C(OCC3=CC=C(C(NC4=CC=CC=C4N)=O)C=C3)C=C2.Cl.Cl

Biological Activity: GK718 is a HDAC1/3 inhibitor (IC50: 259 and 139 nM respectively). GK718 increased acetylated histone H3 level in cells. GK718 inhibits Bleomycin (HY-108345) induced pulmonary fibrosis in mice[1].

Cat. No. Product Name Purity Description Pricing
HY-155329 		GK718 GK718 is a HDAC1/3 inhibitor (IC50: 259 and 139 nM respectively). GK718 increased acetylated histone H3 level in cells. GK718 inhibits Bleomycin (HY-108345) induced pulmonary fibrosis in mice.
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