3033320-00-9
Chemical Structure
Cbl-b-IN-18
- CAS No.: 3033320-00-9
- Formula:C33H31F4N7O
- Molecular Weight:617.64
InChIKey: DJVBWJLHTKAKFE-IBGZPJMESA-N
SMILES: O=C1N(C2=NC(C3CC3)=CC(C4=CC=C(F)C=C4C5=NN=CN5C)=C2)C=NC6=C1C=C(CN7C[C@@H](C)CCC7)C=C6C(F)(F)F
Biological Activity:
Cbl-b-IN-18 (compound 51) is an inhibitor of the E3 ligase Casitas B-lineage lymphoma proto-oncogene B (CPL-B). Cbl-b-IN-18 inhibits the phosphorylation of CPL-B (IC50< 100 nM)[1].
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Cbl-b-IN-18 | Cbl-b-IN-18 (compound 51) is an inhibitor of the E3 ligase Casitas B-lineage lymphoma proto-oncogene B (CPL-B). Cbl-b-IN-18 inhibits the phosphorylation of CPL-B (IC50< 100 nM). |
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Keywords