3033920-95-2
Chemical Structure
Antibiofilm agent-6
- CAS No.: 3033920-95-2
- Formula:C15H12FN3O3
- Molecular Weight:301.27
InChIKey: BPENQBUXUJMKGD-UHFFFAOYSA-N
SMILES: O=C(NNC1=NC2=CC=CC=C2O1)COC3=CC=C(C=C3)F
Biological Activity: Antibiofilm agent-6 (Compound 26c) is a quorum sensing inhibitor with strong antibiofilm effects that can inhibit the fluorescence intensity of PAO1-lasB-gfp and PAO1-pqsA-gfp in a concentration-dependent manner. Antibiofilm agent-6 can inhibit the production of pyocyanin and rhamnolipid. Antibiofilm agent-6 aids helps ciprofloxacin (HY-B0356) effectively eliminate the living bacteria in a mouse model infected with P. aeruginosa PAO1[1].
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Antibiofilm agent-6 | Antibiofilm agent-6 (Compound 26c) is a quorum sensing inhibitor with strong antibiofilm effects that can inhibit the fluorescence intensity of PAO1-lasB-gfp and PAO1-pqsA-gfp in a concentration-dependent manner. Antibiofilm agent-6 can inhibit the production of pyocyanin and rhamnolipid. Antibiofilm agent-6 aids helps ciprofloxacin (HY-B0356) effectively eliminate the living bacteria in a mouse model infected with P. aeruginosa PAO1. | |||||||||||||||||||||
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