3034440-12-2
Chemical Structure
HBV-IN-24
- CAS No.: 3034440-12-2
- Formula:C23H27NO6
- Molecular Weight:413.46
IUPAC Name: hexahydroindolizine-8a(1H)-carboxylic acid
InChIKey: GDEJNWZHQGXKGA-YJBOKZPZSA-N
SMILES: COC1=C(C=C2C[C@H](N3C=C(C(C=C3C2=C1)=O)C(O)=O)C(C)C)OC[C@@H]4CCCO4
Biological Activity: HBV-IN-24 (compound (2ʹS, 6S)-1a) is a potent HBV inhibitor. HBV-IN-24 exhibits potent inhibition activity against HBV DNA, HBsAg, and HBeAg, with EC50 values of 0.6, 0.6, and 4.6 nM, respectively. HBV-IN-24 shows excellent antiviral activity, could have improved neurotoxicity[1].
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HBV-IN-24 | HBV-IN-24 (compound (2ʹS, 6S)-1a) is a potent HBV inhibitor. HBV-IN-24 exhibits potent inhibition activity against HBV DNA, HBsAg, and HBeAg, with EC50 values of 0.6, 0.6, and 4.6 nM, respectively. HBV-IN-24 shows excellent antiviral activity, could have improved neurotoxicity. | |||||||||||||||||||||
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Keywords