3035271-49-6
3035271-49-6
Chemical Structure
Exatecan-3-amine
- CAS No.: 3035271-49-6
- Formula:C24H22FN3O4
- Molecular Weight:435.45
InChIKey: ROTADNRDSNHUAY-GYCJOSAFSA-N
SMILES: N[C@H]1C2=C3C(CC1)=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC3=CC(F)=C2C
Biological Activity: Exatecan-3-amine is an effective exatecan derivative. Exatecan-3-amine can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. Exatecan-3-amine is often combined with CLDN6 mAb to form ADC drugs for the study of tumors with high expression of CLDN6[1].
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Exatecan-3-amine | Exatecan-3-amine is an effective exatecan derivative. Exatecan-3-amine can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. Exatecan-3-amine is often combined with CLDN6 mAb to form ADC drugs for the study of tumors with high expression of CLDN6. | |||||||||||||||||||||
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