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Referencia número: HY-178265

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Exatecan-3-amine

Exatecan-3-amine is an effective exatecan derivative. Exatecan-3-amine can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. Exatecan-3-amine is often combined with CLDN6 mAb to form ADC drugs for the study of tumors with high expression of CLDN6.

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No. CAS: 3035271-49-6
Fòrmula: C₂₄H₂₂FN₃O₄
Peso molecular:435.45

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Exatecan-3-amine Chemical Structure

No. CAS: 3035271-49-6

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Use of MCE Products

One-Stop Platform：From Independent R&D to Pilot-Scale Production

Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas ADC Payloads :

Chemical Information

No. CAS 3035271-49-6
Peso molecular 435.45
Fòrmula C₂₄H₂₂FN₃O₄
SMILES

N[C@H]1C2=C3C(CC1)=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC3=CC(F)=C2C
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Runsheng LI, et al. Preparation of antibodies and antibody-drug conjugates specific to human claudin 6 and their uses for treatment of cancers. WO2024165057.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Exatecan-3-amine

Ver todos los productos específicos de isoformas ADC Payloads

Actividad biológica

Descripciòn

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Exatecan-3-amine Related Classifications

HY-178265 Related Classifications

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Keywords

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