3038178-73-0
3038178-73-0
Chemical Structure
TNIK-IN-9
- CAS No.: 3038178-73-0
- Formula:C24H21N7O3S
- Molecular Weight:487.53
InChIKey: LNYDQACVZRTKLO-XMMPIXPASA-N
SMILES: O[C@@](C1=NC=CS1)(C#CC2=NN3C(N(CCC3)C4=CC=NC(NC5=CC6=C(C=C5)OCO6)=N4)=C2)C
Biological Activity: TNIK-IN-9 (Compound 54) is a selective and potent NIK inhibitor, with an IC50 of 1.27 nM. TNIK-IN-9 can inhibit pro-inflammatory cytokines and nitric oxide production. TNIK-IN-9 exhibits significant anti-inflammatory effects, improved mortality, and hepatoprotective effects in sepsis models[1].
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TNIK-IN-9 | TNIK-IN-9 (Compound 54) is a selective and potent NIK inhibitor, with an IC50 of 1.27 nM. TNIK-IN-9 can inhibit pro-inflammatory cytokines and nitric oxide production. TNIK-IN-9 exhibits significant anti-inflammatory effects, improved mortality, and hepatoprotective effects in sepsis models. | |||||||||||||||||||||
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References
Keywords
