3047675-62-4
Chemical Structure
ERG-IN-5
- CAS No.: 3047675-62-4
- Formula:C23H20F3N7O2
- Molecular Weight:483.45
InChIKey: OUNVECSCHZREFR-UHFFFAOYSA-N
SMILES: NC1=NC(C=CC(C(N(NC(C2CC2)=O)CC3=NC=C(C(F)(F)F)C=C3)=O)=C4)=C4C5=C1C=NN5C
Biological Activity: ERG-IN-5 (Compound M1) is a metabolite of ERG-IN-4 (HY-180918), and it is a hERG potassium channel inhibitor with an IC50 of 1.5 μM. ERG-IN-5 is cytotoxic to MTAPdel HCT116 and its CC50 is 28 nM. ERG-IN-5 can be used for the study of colon cancer[1].
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ERG-IN-5 | ERG-IN-5 (Compound M1) is a metabolite of ERG-IN-4 (HY-180918), and it is a hERG potassium channel inhibitor with an IC50 of 1.5 μM. ERG-IN-5 is cytotoxic to MTAPdel HCT116 and its CC50 is 28 nM. ERG-IN-5 can be used for the study of colon cancer. | |||||||||||||||||||||
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Keywords