3052115-51-9
3052115-51-9
Chemical Structure
SIRT-IN-4
- CAS No.: 3052115-51-9
- Formula:C29H28ClFN4O2
- Molecular Weight:519.01
InChIKey: USLQGCUXEGLWGH-UHFFFAOYSA-N
SMILES: FC1=CC=CC(CN2CCCC(C2)CC3=NC(C4=CC=C(C=C4)NC(C5=CC=C(C=C5)Cl)=O)=NO3)=C1C
Biological Activity: SIRT-IN-4 is an inhibitor of the NAD+-dependent lysine deacetylase Sirtuin2 (Sirt2) (IC50=0.35 μM). SIRT-IN-4 is a potent Sirt2 deacetylase inhibitor that reduces cell survival and inhibits the migration of prostate cancer cells. SIRT-IN-4 can be used to study Sirt2 in cell cycle regulation, gene expression regulation, etc[1].
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SIRT-IN-4 | SIRT-IN-4 is an inhibitor of the NAD+-dependent lysine deacetylase Sirtuin2 (Sirt2) (IC50=0.35 μM). SIRT-IN-4 is a potent Sirt2 deacetylase inhibitor that reduces cell survival and inhibits the migration of prostate cancer cells. SIRT-IN-4 can be used to study Sirt2 in cell cycle regulation, gene expression regulation, etc. | |||||||||||||||||||||
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References
Keywords
