3055766-74-7
3055766-74-7
Chemical Structure
STAT3-IN-36
- CAS No.: 3055766-74-7
- Formula:C30H24F2N2O9S2
- Molecular Weight:658.65
SMILES: O=S(C1=C(OC)C=C(OC)C2=C1OC(C3=CC=C(OC)C(S(=O)(NC4=CC=C(F)C=C4)=O)=C3)=CC2=O)(NC5=CC=C(F)C=C5)=O
Biological Activity: STAT3-IN-36 (compound 11g) is a triple-target inhibitor targeting LRPPRC, STAT3, and CDK1 with anticancer activity. STAT3-IN-36 binds to LRPPRC, STAT3, and CDK1, exerting a stronger anticancer effect than TMF (HY-N6818) or Capecitabine (HY-B0016). STAT3-IN-36 inhibits HGC27 cells with IC50 1.8 μM.[1].
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STAT3-IN-36 | STAT3-IN-36 (compound 11g) is a triple-target inhibitor targeting LRPPRC, STAT3, and CDK1 with anticancer activity. STAT3-IN-36 binds to LRPPRC, STAT3, and CDK1, exerting a stronger anticancer effect than TMF (HY-N6818) or Capecitabine (HY-B0016). STAT3-IN-36 inhibits HGC27 cells with IC50 1.8 μM.. | |||||||||||||||||||||
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