1. Apoptosis
    Epigenetics
    Cell Cycle/DNA Damage
  2. Apoptosis
    Caspase
    PARP
  3. 5,​7,​4'-​Trimethoxyflavone

5,​7,​4'-​Trimethoxyflavone 

Cat. No.: HY-N6818
Handling Instructions

5,7,4'-Trimethoxyflavone is isolated from Kaempferia parviflora (KP) that is a famous medicinal plant from Thailand. 5,7,4'-Trimethoxyflavone induces apoptosis, as evidenced by increments of sub-G1 phase, DNA fragmentation, annexin-V/PI staining, the Bax/Bcl-xL ratio, proteolytic activation of caspase-3, and degradation of poly (ADP-ribose) polymerase (PARP) protein.5,7,4'-Trimethoxyflavone is significantly effective at inhibiting proliferation of SNU-16 human gastric cancer cells in a concentration dependent manner.

For research use only. We do not sell to patients.

5,​7,​4'-​Trimethoxyflavone Chemical Structure

5,​7,​4'-​Trimethoxyflavone Chemical Structure

CAS No. : 5631-70-9

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Description

5,7,4'-Trimethoxyflavone is isolated from Kaempferia parviflora (KP) that is a famous medicinal plant from Thailand. 5,7,4'-Trimethoxyflavone induces apoptosis, as evidenced by increments of sub-G1 phase, DNA fragmentation, annexin-V/PI staining, the Bax/Bcl-xL ratio, proteolytic activation of caspase-3, and degradation of poly (ADP-ribose) polymerase (PARP) protein.5,7,4'-Trimethoxyflavone is significantly effective at inhibiting proliferation of SNU-16 human gastric cancer cells in a concentration dependent manner[1].

IC50 & Target

Caspase-3

 

PARP

 

Molecular Weight

312.32

Formula

C₁₈H₁₆O₅

CAS No.

5631-70-9

SMILES

COC1=C(C(C=C(C2=CC=C(OC)C=C2)O3)=O)C3=CC(OC)=C1

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

5,​7,​4'-​TrimethoxyflavoneApoptosisCaspasePARPpoly ADP ribose polymeraseInhibitorinhibitorinhibit

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5,​7,​4'-​Trimethoxyflavone
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