3094209-58-9
3094209-58-9
Chemical Structure
CDK4 degrader 1
- CAS No.: 3094209-58-9
- Formula:C25H32N8O3S
- Molecular Weight:524.64
InChIKey: PMOKOEHMLYSRLX-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=CN=C(NC3=NC=C(N4CCN(S(=O)(C=C)=O)CC4)C=C3)N=C2N1C5CCCC5)N(C)C
Biological Activity: CDK4 degrader 1 is a selective CDK4 molecular glue degrader. CDK4 degrader 1 induces intracellular CDK4 degradation, and its activity is dependent on DCAF16. CDK4 degrader 1 targets the cysteine residue on DCAF16 through its vinylsulfonylpiperazine domain, thereby mediating the degradation of CDK4. CDK4 degrader 1 can be used in research related to cervical cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
CDK4 degrader 1 | 99.83% | CDK4 degrader 1 is a selective CDK4 molecular glue degrader. CDK4 degrader 1 induces intracellular CDK4 degradation, and its activity is dependent on DCAF16. CDK4 degrader 1 targets the cysteine residue on DCAF16 through its vinylsulfonylpiperazine domain, thereby mediating the degradation of CDK4. CDK4 degrader 1 can be used in research related to cervical cancer. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.81
HY-15777ARibociclib hydrochloride -
Similarity Score 0.81
HY-15777Ribociclib -
Similarity Score 0.79
HY-78751Ribociclib impurity 2 -
Similarity Score 0.78
HY-15777BRibociclib succinate -
Similarity Score 0.74
HY-171459LEQ803 -
Similarity Score 0.72
HY-15777ASRibociclib-d6 hydrochloride -
Similarity Score 0.72
HY-15777SRibociclib-d6 -
Similarity Score 0.71
HY-171459SLEQ803-d3 -
Similarity Score 0.70
HY-164949Ribociclib acetate -
Explore the MedChemAI to find more analogs
