3097167-82-0
3097167-82-0
Chemical Structure
Bfl-1-IN-5
- CAS No.: 3097167-82-0
- Formula:C24H24F3N3O2
- Molecular Weight:443.46
InChIKey: XUNQZBSJKCTTNE-RRMPHLOHSA-N
SMILES: C=CC(N(C1=CC=C(O[C@H]2C[C@H](N)CC2)C=C1)[C@H](C3=CC=C(C(F)(F)F)C(C#N)=C3)C)=O
Biological Activity: Bfl-1-IN-5 (Compound (R,R,S)-26) is a selective inhibitor for Bfl-1 with an IC50 of 0.022 μM. Bfl-1-IN-5 promotes the caspase-3/7 activity with an EC50 of 0.37 μM, and inhibits the cell viability of SU-DHL-1 with an EC50 of 1.3 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Bfl-1-IN-5 | Bfl-1-IN-5 (Compound (R,R,S)-26) is a selective inhibitor for Bfl-1 with an IC50 of 0.022 μM. Bfl-1-IN-5 promotes the caspase-3/7 activity with an EC50 of 0.37 μM, and inhibits the cell viability of SU-DHL-1 with an EC50 of 1.3 μM. | |||||||||||||||||||||
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References
Keywords
