SCD1-IN-1
SCD1-IN-1 is a SCD1 inhibitor (IC50: 5.8 nM). SCD1-IN-1 can be used in the research of dermatologic condition.
For research use only. We do not sell to patients.
- CAS No.: 1111078-63-7
- Formula: C20H20F3NO4
- Molecular Weight:395.37
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
SCD1[1].
SCD1-IN-1 (compound I, 6 days) inhibits the SCD1 enzyme in intact human cells, with an IC50 value of 6.8 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Hamster ear model[1]
-
Dosage:1.5% in a vehicle of propylene glycol/transcutanol/ethanol 20/20/60, w/v, 25 μL.
-
Administration:Applied to ~3 cm2 of the ventral surfaces of both the right and left ears, twice daily for 2 weeks.
-
Result:Resulted in a 62% reduction in CE and an 82% reduction in WE, a mechanism biomarker for sebum production in the hamster model, and a reduction in sebaceous gland size.
Chemical Information
-
CAS No. 1111078-63-7
-
Molecular Weight 395.37
-
Formula C20H20F3NO4
-
SMILES
FC(F)(F)C(C=CC=C1)=C1O[C@@H]2CN(CC2)C(COC3=CC=C(C=C3)CO)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SCD1-IN-1 Related Classifications
HY-150125 Related Classifications
Powered by Bioz