2. Metabolic Enzyme/Protease
  3. Stearoyl-CoA Desaturase (SCD)
  4. SCD1-IN-1

SCD1-IN-1 is a SCD1 inhibitor (IC50: 5.8 nM). SCD1-IN-1 can be used in the research of dermatologic condition.

For research use only. We do not sell to patients.

SCD1-IN-1 Chemical Structure

SCD1-IN-1 Chemical Structure

CAS No. : 1111078-63-7

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

SCD1-IN-1 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

SCD1-IN-1 is a SCD1 inhibitor (IC50: 5.8 nM). SCD1-IN-1 can be used in the research of dermatologic condition[1].

IC50 & Target

SCD1[1].
In Vitro

SCD1-IN-1 (compound I, 6 days) inhibits the SCD1 enzyme in intact human cells, with an IC50 value of 6.8 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SCD1-IN-1 Related Antibodies
In Vivo

SCD1-IN-1 (compound I, 1.5% w/v, 25 μL, applied to surfaces of ears) reduces in cholesterol ester (CE) and wax ester (WE) production in hamster ear model[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Hamster ear model[1]
Dosage: 1.5% in a vehicle of propylene glycol/transcutanol/ethanol 20/20/60, w/v, 25 μL.
Administration: Applied to ~3 cm2 of the ventral surfaces of both the right and left ears, twice daily for 2 weeks.
Result: Resulted in a 62% reduction in CE and an 82% reduction in WE, a mechanism biomarker for sebum production in the hamster model, and a reduction in sebaceous gland size.
Molecular Weight

395.37

Formula

C20H20F3NO4
CAS No.
SMILES

FC(F)(F)C(C=CC=C1)=C1O[C@@H]2CN(CC2)C(COC3=CC=C(C=C3)CO)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

SCD1-IN-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SCD1-IN-11111078-63-7Stearoyl-CoA Desaturase (SCD)Fatty acidsmicrosomalenzymeskinInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
SCD1-IN-1
Cat. No.:
HY-150125
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.