SCD1-IN-1
SCD1-IN-1 is a SCD1 inhibitor (IC50: 5.8 nM). SCD1-IN-1 can be used in the research of dermatologic condition.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 1111078-63-7
- 화학식: C20H20F3NO4
- 분자량:395.37
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
Biological Activity
SCD1[1].
SCD1-IN-1 (compound I, 6 days) inhibits the SCD1 enzyme in intact human cells, with an IC50 value of 6.8 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Hamster ear model[1]
-
Dosage:1.5% in a vehicle of propylene glycol/transcutanol/ethanol 20/20/60, w/v, 25 μL.
-
Administration:Applied to ~3 cm2 of the ventral surfaces of both the right and left ears, twice daily for 2 weeks.
-
Result:Resulted in a 62% reduction in CE and an 82% reduction in WE, a mechanism biomarker for sebum production in the hamster model, and a reduction in sebaceous gland size.
Chemical Information
-
CAS No. 1111078-63-7
-
분자량 395.37
-
화학식 C20H20F3NO4
-
SMILES
FC(F)(F)C(C=CC=C1)=C1O[C@@H]2CN(CC2)C(COC3=CC=C(C=C3)CO)=O
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SCD1-IN-1 Related Classifications
HY-150125 Related Classifications
Powered by Bioz