3107638-80-9
3107638-80-9
Chemical Structure
Fyn-IN-1
- CAS. Nr.: 3107638-80-9
- Formula:C17H14ClN5S
- Molecular Weight:355.84
InChIKey: ZRUUDCBKOCVKNU-UHFFFAOYSA-N
SMILES: CC1=C(N=C(NCC2=CC=NC(Cl)=C2)S1)C3=CNC4=NC=CC=C43
Biological Activity: Fyn-IN-1 (Compound 43) is a selective, blood-brain barrier permeable Fyn and GSK-3β inhibitor with IC50 values of 0.044 μM and 0.61 μM, respectively. Fyn-IN-1 significantly downregulates the pro-inflammatory enzyme iNOS. Fyn-IN-1 can be used in the research of neurodegenerative diseases[1].
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Fyn-IN-1 | Fyn-IN-1 (Compound 43) is a selective, blood-brain barrier permeable Fyn and GSK-3β inhibitor with IC50 values of 0.044 μM and 0.61 μM, respectively. Fyn-IN-1 significantly downregulates the pro-inflammatory enzyme iNOS. Fyn-IN-1 can be used in the research of neurodegenerative diseases. | |||||||||||||||||||||
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