Fyn-IN-1
Fyn-IN-1 (Compound 43) is a selective, blood-brain barrier permeable Fyn and GSK-3β inhibitor with IC50 values of 0.044 μM and 0.61 μM, respectively. Fyn-IN-1 significantly downregulates the pro-inflammatory enzyme iNOS. Fyn-IN-1 can be used in the research of neurodegenerative diseases.
For research use only. We do not sell to patients.
- CAS No.: 3107638-80-9
- Formula: C17H14ClN5S
- Molecular Weight:355.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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GSK-3β 0.61 μM (IC50) |
iNOS |
Fyn 0.044 μM (IC50) |
Chemical Information
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CAS No. 3107638-80-9
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Molecular Weight 355.84
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Formula C17H14ClN5S
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SMILES
CC1=C(N=C(NCC2=CC=NC(Cl)=C2)S1)C3=CNC4=NC=CC=C43
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)