3107808-75-0
Chemical Structure
NOTA-Asp2-αvβ6L
- CAS. Nr.: 3107808-75-0
- Formula:C77H115N19O27
- Molecular Weight:1738.85
InChIKey: PAAWZXKBULJZMT-FGTYGRSASA-N
SMILES: O=C([C@H](CC(O)=O)NC(CN1)=O)N[C@H](C(N[C@@H](C)C(N[C@@H](CC2=CC=C(C=C2)O)C(N3CCC[C@]3([H])C(N([C@H](C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@H](C1=O)CCCNC(N)=N)=O)=O)CCCCNC(COCCOCCNC([C@H](CC(O)=O)NC([C@H](CC(O)=O)NC(CN5CCN(CCN(CC5)CC(O)=O)CC(O)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)CC(C)C
Biological Activity: NOTA-Asp2-αvβ6L is an integrin αvβ6 binder with selective accumulation in αvβ6-positive pancreatic cancer cells and tumors. NOTA-Asp2-αvβ6L can be used as a PET/CT tracer for imaging pancreatic ductal adenocarcinoma (PDAC)[1].
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NOTA-Asp2-αvβ6L | NOTA-Asp2-αvβ6L is an integrin αvβ6 binder with selective accumulation in αvβ6-positive pancreatic cancer cells and tumors. NOTA-Asp2-αvβ6L can be used as a PET/CT tracer for imaging pancreatic ductal adenocarcinoma (PDAC). | |||||||||||||||||||||
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Keywords
