3116709-87-3
3116709-87-3
Chemical Structure
VEGFR-2-IN-64
- CAS No.: 3116709-87-3
- Formula:C72H123N9O6
- Molecular Weight:1210.80
InChIKey: CGFCVRAJWNQSDJ-UHFFFAOYSA-N
SMILES: O=C(OCC1=CN(N=N1)CCCCCCCCCCCCCCCCCC)C2=CC(C(OCC3=CN(N=N3)CCCCCCCCCCCCCCCCCC)=O)=CC(C(OCC4=CN(N=N4)CCCCCCCCCCCCCCCCCC)=O)=C2
Biological Activity: VEGFR-2-IN-64 (Compound 28) is the inhibitor for VEGFR2 with IC50 of 27.8 nM. VEGFR-2-IN-64 inhibits the proliferation of cancer cell A549, T-47D and Caco-2, exhibits anti-migration and anti-cloning activities in cell T-47D, induces apoptosis in T-47D[1].
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VEGFR-2-IN-64 | VEGFR-2-IN-64 (Compound 28) is the inhibitor for VEGFR2 with IC50 of 27.8 nM. VEGFR-2-IN-64 inhibits the proliferation of cancer cell A549, T-47D and Caco-2, exhibits anti-migration and anti-cloning activities in cell T-47D, induces apoptosis in T-47D. | |||||||||||||||||||||
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References
Keywords
