314761-14-3
314761-14-3
Chemical Structure
BTSA1
- CAS. Nr.: 314761-14-3
- Formula:C21H14N6OS2
- Molecular Weight:430.51
IUPAC Name: (E)-5-phenyl-2-(4-phenylthiazol-2-yl)-4-(2-(thiazol-2-yl)hydrazono)-2,4-dihydro-3H-pyrazol-3-one
InChIKey: KYVZVVOQWWCVPP-HKOYGPOVSA-N
SMILES: O=C(N(C1=NC(C2=CC=CC=C2)=CS1)N=C/3C4=CC=CC=C4)C3=N\NC5=NC=CS5
Biological Activity: BTSA1 is a potent, high affinity and orally active BAX activator with an IC50 of 250 nM and an EC50 of 144 nM. BTSA1 binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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BTSA1 | 99.77% | BTSA1 is a potent, high affinity and orally active BAX activator with an IC50 of 250 nM and an EC50 of 144 nM. BTSA1 binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. | ||||||||||||||||||||
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Structural Analogs
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