315702-79-5
Chemical Structure
CS-1-69
- CAS No.: 315702-79-5
- Formula:C14H11N3OS
- Molecular Weight:269.32
IUPAC Name: 4-((4-(pyridin-2-yl)thiazol-2-yl)amino)phenol
InChIKey: GLAADHPXEHHDBC-UHFFFAOYSA-N
SMILES: OC1=CC=C(NC2=NC(C3=NC=CC=C3)=CS2)C=C1
Biological Activity: CS-1-69 is an MBD2 ligand analog that does not bind to individual NuRD components MBD2 or HDAC1, but binds robustly to the assembled NuRD complex (MBD2, HDAC1, and MT1A) in a dose-responsive manner. CS-1-69 attenuates Transcriptional Repression via Active Chemical Epigenetic Reprogrammin (TRACER)-mediated strogen receptor (ER) inhibitory activity[1].
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CS-1-69 | CS-1-69 is an MBD2 ligand analog that does not bind to individual NuRD components MBD2 or HDAC1, but binds robustly to the assembled NuRD complex (MBD2, HDAC1, and MT1A) in a dose-responsive manner. CS-1-69 attenuates Transcriptional Repression via Active Chemical Epigenetic Reprogrammin (TRACER)-mediated strogen receptor (ER) inhibitory activity. | |||||||||||||||||||||
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Keywords
