328946-18-5
Chemical Structure
1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d22
Synonym(s): DHPC-d22
- CAS No.: 328946-18-5
- Formula:C20H18D22NO8P
- Molecular Weight:475.64
IUPAC Name: (3S,7S,8S,9S,10R,13R,14S,17R)-17-((2R)-5-hydroxy-6-(methyl-d3)heptan-2-yl-6,7,7,7-d4)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
InChIKey: DVZARZBAWHITHR-BGBVYDDGSA-N
SMILES: C[N+](C)(C)CCOP(OC[C@@H](COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)([O-])=O
Biological Activity: 1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d22 (DHPC-d22) is the deuterated-labeled 1,2-Dihexanoyl-sn-glycero-3-phosphocholine (HY-W127457). 1,2-Dihexanoyl-sn-glycero-3-phosphocholine (DHPC) is a short-chain zwitterionic phosphatidylcholine analog. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine is a substrate of phospholipase D and can be hydrolyzed to support transphosphatidylation reactions. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine binds to the C2 domain of cPLA2α and interacts with Ca2+, Asn65, and Tyr96, mediating the domain's recognition of phosphatidylcholine. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine can be used in organic synthesis-related research, such as the generation of micelles, liposomes, and other types of artificial membranes[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d22 | 99.0% | 1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d22 (DHPC-d22) is the deuterated-labeled 1,2-Dihexanoyl-sn-glycero-3-phosphocholine (HY-W127457). 1,2-Dihexanoyl-sn-glycero-3-phosphocholine (DHPC) is a short-chain zwitterionic phosphatidylcholine analog. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine is a substrate of phospholipase D and can be hydrolyzed to support transphosphatidylation reactions. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine binds to the C2 domain of cPLA2α and interacts with Ca2+, Asn65, and Tyr96, mediating the domain's recognition of phosphatidylcholine. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine can be used in organic synthesis-related research, such as the generation of micelles, liposomes, and other types of artificial membranes. | ||||||||||||||||||||
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1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d31 | 1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d31 (DHPC-d31) is the deuterated-labeled 1,2-Dihexanoyl-sn-glycero-3-phosphocholine (HY-W127457). 1,2-Dihexanoyl-sn-glycero-3-phosphocholine (DHPC) is a short-chain zwitterionic phosphatidylcholine analog. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine is a substrate of phospholipase D and can be hydrolyzed to support transphosphatidylation reactions. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine binds to the C2 domain of cPLA2α and interacts with Ca2+, Asn65, and Tyr96, mediating the domain's recognition of phosphatidylcholine. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine can be used in organic synthesis-related research, such as the generation of micelles, liposomes, and other types of artificial membranes. | |||||||||||||||||||||
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1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d9 | 1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d9 (DHPC-d9) is the deuterated-labeled 1,2-Dihexanoyl-sn-glycero-3-phosphocholine (HY-W127457). 1,2-Dihexanoyl-sn-glycero-3-phosphocholine (DHPC) is a short-chain zwitterionic phosphatidylcholine analog. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine is a substrate of phospholipase D and can be hydrolyzed to support transphosphatidylation reactions. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine binds to the C2 domain of cPLA2α and interacts with Ca2+, Asn65, and Tyr96, mediating the domain's recognition of phosphatidylcholine. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine can be used in organic synthesis-related research, such as the generation of micelles, liposomes, and other types of artificial membranes. | |||||||||||||||||||||
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1,2-Dihexanoyl-sn-glycero-3-phosphocholine | 99.93% | 1,2-Dihexanoyl-sn-glycero-3-phosphocholine (DHPC) is a short-chain zwitterionic phosphatidylcholine analog. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine is a substrate of phospholipase D and can be hydrolyzed to support transphosphatidylation reactions. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine binds to the C2 domain of cPLA2α and interacts with Ca2+, Asn65, and Tyr96, mediating the domain's recognition of phosphatidylcholine. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine can be used in organic synthesis-related research, such as the generation of micelles, liposomes, and other types of artificial membranes. | ||||||||||||||||||||
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References
- [1]. Hirano Y, et al. Structural basis of phosphatidylcholine recognition by the C2-domain of cytosolic phospholipase A₂α. eLife, 2019.
- [2]. Van der Heyden A, et al. Grafted dinuclear zinc complexes for selective recognition of phosphatidylserine: Application to the capture of extracellular membrane microvesicles. Journal of Inorganic Biochemistry, 2023.
- [3]. Davis LL, et al. Phospholipase D hydrolyzes short-chain analogs of phosphatidylcholine in the absence of detergent. Lipids. 1998 Feb;33(2):223-7.
