329706-62-9
Chemical Structure
AG6033
- CAS No.: 329706-62-9
- Formula:C30H23N5O4
- Molecular Weight:517.53
IUPAC Name: (Z)-N-(3-(2-(2-oxo-1-(2-oxo-2-(phenylamino)ethyl)indolin-3-ylidene)hydrazine-1-carbonyl)phenyl)benzamide
InChIKey: DUXIDJFLWMQRQM-KGGMANCPSA-N
SMILES: O=C(N/N=C1C(N(CC(NC2=CC=CC=C2)=O)C3=C\1C=CC=C3)=O)C4=CC=CC(NC(C5=CC=CC=C5)=O)=C4
Biological Activity: AG6033 is a potential novel CRBN modulator. AG6033 suppresses various tumor cells by modulating the interactions between CRBN and various antitumor target proteins. AG6033 can cause GSPT1 and IKZF1 degradation. AG6033 induces CRBN-dependent cytotoxic effect[1].
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AG6033 | AG6033 is a potential novel CRBN modulator. AG6033 suppresses various tumor cells by modulating the interactions between CRBN and various antitumor target proteins. AG6033 can cause GSPT1 and IKZF1 degradation. AG6033 induces CRBN-dependent cytotoxic effect. | |||||||||||||||||||||
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Keywords
