33414-33-4
33414-33-4
Chemical Structure
Ethacizine
- CAS No.: 33414-33-4
- Formula:C22H27N3O3S
- Molecular Weight:413.53
IUPAC Name: ethyl (10-(3-(diethylamino)propanoyl)-10H-phenothiazin-2-yl)carbamate
InChIKey: PQXGNJKJMFUPPM-UHFFFAOYSA-N
SMILES: O=C(OCC)NC(C=C1N2C(CCN(CC)CC)=O)=CC=C1SC3=C2C=CC=C3
Biological Activity: Ethacizine is an antiarrhythmic agent and analog of Ethmozine (HY-B0615A). Ethacizine inhibits ventricular premature beats[1][2][3][4].
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Ethacizine | Ethacizine is an antiarrhythmic agent and analog of Ethmozine (HY-B0615A). Ethacizine inhibits ventricular premature beats. | |||||||||||||||||||||
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Ethacizine-d4 | Ethacizine-d4 is the d4-labeled Ethacizine (HY-131987). Ethacizine is an antiarrhythmic agent and analog of Ethmozine (HY-B0615A). Ethacizine inhibits ventricular premature beats. | |||||||||||||||||||||
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Ethacizine-d5 | 98.00% | Ethacizine-d5 is the d5-labeled Ethacizine (HY-131987). Ethacizine is an antiarrhythmic agent and analog of Ethmozine (HY-B0615A). Ethacizine inhibits ventricular premature beats. | ||||||||||||||||||||
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References
- [1]. Smetnev AS, et al. Clinical, electrophysiologic and antiarrhythmic efficacy of moricizine HCl. The American journal of cardiology. 1987 Oct 16;60(11):40F-44F.
- [2]. Baldenkov GN, et al. Action of ethmozine and ethacizine on dopaminergic adenylate cyclase of the brain striatal system. Bulletin of Experimental Biology and Medicine. 1984 Oct;98(4):1377-80.
- [3]. Kukes VG, et al. A new Soviet drug, ethacizine, in the treatment of ventricular rhythm disorders. Kardiologiia. 1983 Nov;23(11):45-7. Russian.
- [4]. Karaush AP, et al. Effectiveness of single intravenous administration of cordarone, ethacizine and obsidan in ventricular extrasystole in patients with chronic alcoholism during withdrawal. Kardiologiia. 1991 Jan;31(1):65-6. Russian.
