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Cat. No.: HY-131987

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Ethacizine

Name: Ethacizine
Brand: MedChemExpress
SKU: HY-131987
Availability: PreOrder

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Ethacizine is an antiarrhythmic agent and analog of Ethmozine (HY-B0615A). Ethacizine inhibits ventricular premature beats.

For research use only. We do not sell to patients.

CAS No.: 33414-33-4
Formula: C₂₂H₂₇N₃O₃S
Molecular Weight:413.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Ethacizine Chemical Structure

CAS No.: 33414-33-4

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Other In-stock Forms of Ethacizine

Ethacizine hydrochloride

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- In Vitro
Chemical Information
Publications (1)
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Biological Activity

Description

Ethacizine is an antiarrhythmic agent and analog of Ethmozine (HY-B0615A). Ethacizine inhibits ventricular premature beats^[1]^[2]^[3]^[4].

In Vitro

Ethacizine (5 μM; 10 min) shows low affinity for dopamine D-1-coupled adenylate cyclase in rabbit striatal membranes after 10 min of action at 37°C (inhibition constant = 4 μM), and only weakly inhibits dopamine-stimulated cAMP production^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 33414-33-4
Molecular Weight 413.53
Formula C₂₂H₂₇N₃O₃S
SMILES

O=C(OCC)NC(C=C1N2C(CCN(CC)CC)=O)=CC=C1SC3=C2C=CC=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Chem Pap

2026 Apr 3.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Smetnev AS, et al. Clinical, electrophysiologic and antiarrhythmic efficacy of moricizine HCl. The American journal of cardiology. 1987 Oct 16;60(11):40F-44F.

[2]. Baldenkov GN, et al. Action of ethmozine and ethacizine on dopaminergic adenylate cyclase of the brain striatal system. Bulletin of Experimental Biology and Medicine. 1984 Oct;98(4):1377-80.

[3]. Kukes VG, et al. A new Soviet drug, ethacizine, in the treatment of ventricular rhythm disorders. Kardiologiia. 1983 Nov;23(11):45-7. Russian.

[4]. Karaush AP, et al. Effectiveness of single intravenous administration of cordarone, ethacizine and obsidan in ventricular extrasystole in patients with chronic alcoholism during withdrawal. Kardiologiia. 1991 Jan;31(1):65-6. Russian.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- In Vitro
Chemical Information
Publications (1)
Purity & Documentation
References

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