334994-34-2
334994-34-2
Chemical Structure
Norleual
- CAS No.: 334994-34-2
- Formula:C41H58N8O7
- Molecular Weight:774.95
IUPAC Name: ((S)-2-((S)-2-((S)-2-aminohexanamido)-3-(4-hydroxyphenyl)propanamido)-4-methylpentyl)-L-histidyl-L-prolyl-L-phenylalanine
InChIKey: LOHDEFSMLITXTG-VCAFKBFISA-N
SMILES: O=C(N(CCC1)[C@@H]1C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)[C@@H](NC[C@H](CC(C)C)NC([C@@H](NC([C@@H](N)CCCC)=O)CC(C=C3)=CC=C3O)=O)CC4=CN=CN4
Biological Activity: Norleual, an angiotensin (Ang) IV analog, is a hepatocyte growth factor (HGF)/c-Met inhibitor with an IC50 of 3 pM. Norleual is an AT4 receptor antagonist and exhibits potent antiangiogenic activities[1].
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Norleual | Norleual, an angiotensin (Ang) IV analog, is a hepatocyte growth factor (HGF)/c-Met inhibitor with an IC50 of 3 pM. Norleual is an AT4 receptor antagonist and exhibits potent antiangiogenic activities. | |||||||||||||||||||||
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