339163-65-4

RCM-1 Chemical Structure
339163-65-4

Chemical Structure

RCM-1

  • CAS No.: 339163-65-4
  • Formula:C20H12N2OS4
  • Molecular Weight:424.58

IUPAC Name: 2-((2-oxo-2-(thiophen-2-yl)ethyl)thio)-4,6-di(thiophen-2-yl)nicotinonitrile

InChIKey: DCCYTKKDAZEVLY-UHFFFAOYSA-N

SMILES: N#CC1=C(C2=CC=CS2)C=C(C3=CC=CS3)N=C1SCC(C4=CC=CS4)=O

Biological Activity: RCM-1 is a forkhead box M1 (FOXM1) inhibitor with an EC50 of 0.72 μM in U2OS cells. RCM-1 blocks the nuclear localization and increased the proteasomal degradation of FOXM1. RCM-1 can be used for asthma and other chronic airway diseases research[1].

Cat. No. Nom du produit Pureté Description Pricing
HY-19979 		RCM-1 98.56% RCM-1 is a forkhead box M1 (FOXM1) inhibitor with an EC50 of 0.72 μM in U2OS cells. RCM-1 blocks the nuclear localization and increased the proteasomal degradation of FOXM1. RCM-1 can be used for asthma and other chronic airway diseases research.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

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