339163-65-4
339163-65-4
Chemical Structure
RCM-1
- CAS No.: 339163-65-4
- Formula:C20H12N2OS4
- Molecular Weight:424.58
IUPAC Name: 2-((2-oxo-2-(thiophen-2-yl)ethyl)thio)-4,6-di(thiophen-2-yl)nicotinonitrile
InChIKey: DCCYTKKDAZEVLY-UHFFFAOYSA-N
SMILES: N#CC1=C(C2=CC=CS2)C=C(C3=CC=CS3)N=C1SCC(C4=CC=CS4)=O
Biological Activity: RCM-1 is a forkhead box M1 (FOXM1) inhibitor with an EC50 of 0.72 μM in U2OS cells. RCM-1 blocks the nuclear localization and increased the proteasomal degradation of FOXM1. RCM-1 can be used for asthma and other chronic airway diseases research[1].
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RCM-1 | 98.56% | RCM-1 is a forkhead box M1 (FOXM1) inhibitor with an EC50 of 0.72 μM in U2OS cells. RCM-1 blocks the nuclear localization and increased the proteasomal degradation of FOXM1. RCM-1 can be used for asthma and other chronic airway diseases research. | ||||||||||||||||||||
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References
Keywords
