34031-32-8
34031-32-8
Chemical Structure
Auranofin
Synonym(s): SKF-39162
- CAS No.: 34031-32-8
- Formula:C20H34AuO9PS
- Molecular Weight:678.48
InChIKey: AUJRCFUBUPVWSZ-XTZHGVARSA-M
SMILES: CC(O[C@@H]([C@@H]([C@H]1COC(C)=O)OC(C)=O)[C@H]([C@@H](O1)[S-][Au+][P](CC)(CC)CC)OC(C)=O)=O
Biological Activity: Auranofin (SKF-39162) is a thioredoxin reductase (TrxR) inhibitor with an IC50 of 0.2 μM. Auranofin exhibits antiviral activity against SARS-CoV21, with a CC50 of 4.2 μM for monkey kidney Vero E6 cells.
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Auranofin | 99.71% | Auranofin (SKF-39162) is a thioredoxin reductase (TrxR) inhibitor with an IC50 of 0.2 μM. Auranofin exhibits antiviral activity against SARS-CoV21, with a CC50 of 4.2 μM for monkey kidney Vero E6 cells. | ||||||||||||||||||||
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Auranofin (Standard) | ≥98% | Auranofin (Standard) is the analytical standard of Auranofin. This product is intended for research and analytical applications. Auranofin (SKF-39162) is a thioredoxin reductase (TrxR) inhibitor with an IC50 of 0.2 μM. Auranofin exhibits antiviral activity against SARS-CoV21, with a CC50 of 4.2 μM for monkey kidney Vero E6 cells. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.69
HY-W0398651-Thio-beta-D-glucose tetraacetate -
Similarity Score 0.69
HY-W039848α-D-Glucopyranoside,ethyl 1-thio,2,3,4,6-tetraacetate -
Similarity Score 0.69
HY-W317473Ethyl 1-thio-β-D-galactopyranoside tetraacetate -
Similarity Score 0.69
HY-W332536α-D-Galactopyranoside,ethyl 1-thio,2,3,4,6-tetraacetate -
Similarity Score 0.69
HY-W410950α-D-Mannopyranoside,ethyl 1-thio,2,3,4,6-tetraacetate -
Similarity Score 0.68
HY-W102386Methyl 2,3,4,6-Tetra-O-acetyl-1-thio-α-D-mannopyranoside -
Similarity Score 0.68
HY-W144406Methyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranoside -
Similarity Score 0.68
HY-W145691Methyl 2,3,4,6-tetra-O-acetyl-β-D-thiogalactopyranoside -
Similarity Score 0.67
HY-W555447(2R,3S,4S,5R,6S)-2-(Acetoxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triyl triacetate -
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