34387-64-9
34387-64-9
Chemical Structure
PET-16
- CAS 番号: 34387-64-9
- Formula:C26H20BrP
- Molecular Weight:443.31
IUPAC Name: triphenyl(phenylethynyl)phosphonium bromide
InChIKey: QVTSWQFDFUAKJQ-UHFFFAOYSA-M
SMILES: C1(C#C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)=CC=CC=C1.[Br-]
Biological Activity: PET-16 is a selective HSP70 inhibitor that binds to an allosteric pocket of the substrate-binding domain. PET-16 inhibits the ability of HSP70 to cycle between ATP-bound and ADP-bound states. PET-16 induces apoptosis in multiple myeloma[1].
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PET-16 | 98.07% | PET-16 is a selective HSP70 inhibitor that binds to an allosteric pocket of the substrate-binding domain. PET-16 inhibits the ability of HSP70 to cycle between ATP-bound and ADP-bound states. PET-16 induces apoptosis in multiple myeloma. | ||||||||||||||||||||
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