353519-63-8
353519-63-8
Chemical Structure
HLM006474
- CAS No.: 353519-63-8
- Formula:C25H25N3O2
- Molecular Weight:399.48
IUPAC Name: 7-((4-ethoxy-3-methylphenyl)(pyridin-2-ylamino)methyl)-2-methylquinolin-8-ol
InChIKey: CYNZBLNMIJNBSF-UHFFFAOYSA-N
SMILES: OC(C1=NC(C)=CC=C1C=C2)=C2C(NC3=NC=CC=C3)C(C=C4C)=CC=C4OCC
Biological Activity: HLM006474 is a pan E2F inhibitor, which inhibits E2F4 DNA-binding with an IC50 of 29.8 μM in A375 cells.
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HLM006474 | 98.44% | HLM006474 is a pan E2F inhibitor, which inhibits E2F4 DNA-binding with an IC50 of 29.8 μM in A375 cells. | ||||||||||||||||||||
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Keywords
