354812-16-1
Chemical Structure
AA43279
- CAS No.: 354812-16-1
- Formula:C12H12N2O2S
- Molecular Weight:248.31
IUPAC Name: 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxamide
InChIKey: OEUITKOCUWEFOB-UHFFFAOYSA-N
SMILES: O=C(C1=C(N)C=C(C2=CC=C(OC)C=C2)S1)N
Biological Activity: AA43279 is an in gamma-aminobutyric acid (GABA) fast-firing interneurons located activator for Nav1.1 channel (SCN1A) with an EC50 of 9.5 μM. AA43279 enhances specific neuronal firing activity in vitro, and exhibits anticonvulsant activity in rat MEST model[1].
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AA43279 | 98.00% | AA43279 is an in gamma-aminobutyric acid (GABA) fast-firing interneurons located activator for Nav1.1 channel (SCN1A) with an EC50 of 9.5 μM. AA43279 enhances specific neuronal firing activity in vitro, and exhibits anticonvulsant activity in rat MEST model. | ||||||||||||||||||||
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Keywords