356559-13-2
356559-13-2
Chemical Structure
SB-505124 hydrochloride
- CAS No.: 356559-13-2
- Formula:C20H22ClN3O2
- Molecular Weight:371.86
IUPAC Name: 2-(4-(benzo[d][1,3]dioxol-5-yl)-2-(tert-butyl)-1H-imidazol-5-yl)-6-methylpyridine hydrochloride
InChIKey: BTUOOXPZOVNPMF-UHFFFAOYSA-N
SMILES: CC1=CC=CC(C2=C(C3=CC=C(OCO4)C4=C3)N=C(C(C)(C)C)N2)=N1.[H]Cl
Biological Activity: SB-505124 hydrochloride is a selective inhibitor of TGF-β Receptor type I receptor (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SB-505124 hydrochloride | 98.52% | SB-505124 hydrochloride is a selective inhibitor of TGF-β Receptor type I receptor (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6. | ||||||||||||||||||||
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SB-505124 hydrochloride (Standard) | ≥98% | SB-505124 (hydrochloride) (Standard) is the analytical standard of SB-505124 (hydrochloride). This product is intended for research and analytical applications. SB-505124 hydrochloride is a selective inhibitor of TGF-β Receptor type I receptor (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-13521SB-505124 -
Similarity Score 0.67
HY-111482SM 16 -
Similarity Score 0.65
HY-126463LolCDE-IN-4 -
Similarity Score 0.64
HY-12043SB 525334 -
Similarity Score 0.58
HY-10431GSB-431542 (GMP) -
Similarity Score 0.54
HY-10324RD4476 (Standard) -
Similarity Score 0.53
HY-169788Graveolinine -
Similarity Score 0.53
HY-187000α-Synuclein ligand-1 -
Similarity Score 0.53
HY-101855REmrusolmin (Standard) -
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