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Cat. No.: HY-169788

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Graveolinine

Graveolinine is a quinoline alkaloid, that can be isolated from Ruta chalepensis. Graveolinine exhibits antiplatelet activity, that reduces Arachidonic Acid (HY-109590)- and Collagen-induced aggregation of washed rabbit platelets.

For research use only. We do not sell to patients.

CAS No.: 4179-37-7
Formula: C₁₇H₁₃NO₃
Molecular Weight:279.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Graveolinine Chemical Structure

CAS No.: 4179-37-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	>50 μM Compound: Graveolinine	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 31744779]
PC-12	IC₅₀	>50 μM Compound: Graveolinine	Cytotoxicity against rat PC12 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against rat PC12 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 31744779]

Chemical Information

CAS No. 4179-37-7
Molecular Weight 279.29
Formula C₁₇H₁₃NO₃
SMILES

COC1=CC(C2=CC3=C(OCO3)C=C2)=NC4=C1C=CC=C4
Structure Classification
- Alkaloids
- Quinoline Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ulubelen A, et al., Alkaloids and coumarins from the roots of Ruta chalepensis var. latifolia. Planta Med. 1988 Dec;54(6):551-2. [Content Brief]

[2]. Wu T S, et al. Cytotoxic and antiplatelet aggregation principles of Ruta graveolens[J]. Journal of the Chinese chemical society, 2003, 50(1): 171-178.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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