3922-90-5
Chemical Structure
Oleandomycin
- CAS No.: 3922-90-5
- Formula:C35H61NO12
- Molecular Weight:687.86
IUPAC Name: (3R,5R,6S,7R,8R,11R,12S,13R,14S,15S)-14-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-hydroxy-12-(((2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5,7,8,11,13,15-hexamethyl-1,9-dioxaspiro[2.13]hexadecane-4,10-dione
InChIKey: RZPAKFUAFGMUPI-QESOVKLGSA-N
SMILES: O=C1[C@H](C)[C@@H](O)[C@@H](C)[C@@H](C)OC([C@H](C)[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](OC)C2)[C@H](C)[C@@H](O[C@@]3([H])[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3)[C@@H](C)C[C@@]14CO4)=O
Biological Activity: Oleandomycin is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Oleandomycin | 99.84% | Oleandomycin is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes. | ||||||||||||||||||||
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Troleandomycin | 99.30% | Troleandomycin (Triacetyloleandomycin), a macrolide acrolide antibiotic, is a selective CYP3A inhibitor. Troleandomycin is an oral corticosteroid for asthma study. | ||||||||||||||||||||
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Oleandomycin phosphate | Oleandomycin phosphate is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes. | |||||||||||||||||||||
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Erythromycin C | 98.78% | Erythromycin C is an antibiotic. Erythromycin C could be isolated from the fermentation process of the penicillium Streptomyces erythreus. | ||||||||||||||||||||
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Erythromycin | 98.0% | Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research. | ||||||||||||||||||||
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Erythromycin hydrochloride | Erythromycin hydrochloride is a protein synthesis inhibitor with activity against the growth of both Gram-negative and Gram-positive bacteria. Erythromycin hydrochloride is commonly used in biomedicine to inhibit diseases caused by bacterial infections. Erythromycin hydrochloride is also involved in the inhibition of mammalian mRNA splicing. The application range of erythromycin hydrochloride includes respiratory tract infections, skin infections, and other infections caused by sensitive bacteria. | |||||||||||||||||||||
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Erythromycin-13C2 | Erythromycin-13C2 is a macrolide antibiotic that can be used to treat respiratory infections, skin infections, and chlamydia infections. | |||||||||||||||||||||
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Erythromycin B | 95.0% | Erythromycin B has anti-malarial activity and effectively inhibits the asexual reproduction of Plasmodium falciparum. | ||||||||||||||||||||
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Erythromycin impurity 6 | Erythromycin impurity 6 is an impurity of Erythromycin. | |||||||||||||||||||||
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Erythromycin impurity 5 | Erythromycin impurity 5 is an impurity of Erythromycin. | |||||||||||||||||||||
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Clarithromycin impurity 2 | Clarithromycin impurity 2 is an impurity of Clarithromycin. | |||||||||||||||||||||
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References
- [1]. Vilches C, et al. Role of glycosylation and deglycosylation in biosynthesis of and resistance to oleandomycin in the producer organism, Streptomyces antibioticus. J Bacteriol. 1992 Jan;174(1):161-5. [Content Brief]
- [2]. Semenitz E, et al. The antibacterial activity of oleandomycin and erythromycin--a comparative investigation using microcalorimetry and MIC determination. J Antimicrob Chemother. 1978 Sep;4(5):455-7. [Content Brief]
