410074-73-6
410074-73-6
Chemical Structure
Amitifadine
Synonym(s): DOV-21947; EB-1010
- CAS No.: 410074-73-6
- Formula:C11H11Cl2N
- Molecular Weight:228.12
IUPAC Name: (1R,5S)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane
InChIKey: BSMNRYCSBFHEMQ-KCJUWKMLSA-N
SMILES: ClC1=C(Cl)C=CC([C@]23[C@](CNC3)([H])C2)=C1
Biological Activity: Amitifadine (DOV-21947; EB-1010) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI), with IC50s of 12, 23, 96 nM for serotonin, norepinephrine and dopamine in HEK 293 cells , respectively.
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Amitifadine | Amitifadine (DOV-21947; EB-1010) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI), with IC50s of 12, 23, 96 nM for serotonin, norepinephrine and dopamine in HEK 293 cells , respectively. | |||||||||||||||||||||
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Keywords
