420106-23-6
420106-23-6
Chemical Structure
ATXN1-MED15 PPI-IN-1
- CAS No.: 420106-23-6
- Formula:C29H21NO4
- Molecular Weight:447.48
InChIKey: XNYMPHBZSUCWTP-KNTRCKAVSA-N
SMILES: O=C(/C=C/C1=CC=C(NC(C2=C(C3=CC=CC=C3C(O)=O)C=CC=C2)=O)C=C1)C4=CC=CC=C4
Biological Activity: ATXN1-MED15 PPI-IN-1 (compound 5755483) is an inhibitor of ATXN1/MED15. ATXN1-MED15 PPI-IN-1 binds to ATXN1 residues 99-163 and inhibits both the interaction between ATXN1 and MED15, as well as the dimerization of polyQ-expanded ATXN1. ATXN1-MED15 PPI-IN-1 can be used for study of Spinocerebellar ataxia type 1[1].
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ATXN1-MED15 PPI-IN-1 | ATXN1-MED15 PPI-IN-1 (compound 5755483) is an inhibitor of ATXN1/MED15. ATXN1-MED15 PPI-IN-1 binds to ATXN1 residues 99-163 and inhibits both the interaction between ATXN1 and MED15, as well as the dimerization of polyQ-expanded ATXN1. ATXN1-MED15 PPI-IN-1 can be used for study of Spinocerebellar ataxia type 1. | |||||||||||||||||||||
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References
Keywords
