454234-24-3
454234-24-3
Chemical Structure
JAK3-IN-14
- CAS No.: 454234-24-3
- Formula:C18H13N3O
- Molecular Weight:287.32
InChIKey: IQNTXIMXKCURDC-YBEGLDIGSA-N
SMILES: O=C1NC2=CC=C(C3=CN=CC=C3)C=C2/C1=C/C4=CC=CN4
Biological Activity: JAK3-IN-14 (compound 1) is a potent JAK3 inhibitor, with IC50 values of 38 and 600 nM for JAK3 and JAK2, respectively. JAK3-IN-14 shows inhibitory of IL-4 and IL-3 induced TF-1 cell proliferation, with IC50 values of 600 and 500 nM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JAK3-IN-14 | 99.10% | JAK3-IN-14 (compound 1) is a potent JAK3 inhibitor, with IC50 values of 38 and 600 nM for JAK3 and JAK2, respectively. JAK3-IN-14 shows inhibitory of IL-4 and IL-3 induced TF-1 cell proliferation, with IC50 values of 600 and 500 nM, respectively. | ||||||||||||||||||||
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References
Keywords
