458151-38-7
458151-38-7
Chemical Structure
CRBN ligand-678
- CAS No.: 458151-38-7
- Formula:C17H13N3O4
- Molecular Weight:323.31
IUPAC Name: 5-amino-2-(2,6-dioxopiperidin-3-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
InChIKey: AIQPKXWIKLCGGM-UHFFFAOYSA-N
SMILES: O=C1NC(=O)C(N2C(=O)C=3C=CC=C4C=C(N)C=C(C2=O)C43)CC1
Biological Activity: CRBN ligand-678 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-678 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-678 | CRBN ligand-678 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-678 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords
