459-80-3
Chemical Structure
Geranic acid
Synonym(s): Geranate; NSC 229335; GAGE
- CAS No.: 459-80-3
- Formula:C10H16O2
- Molecular Weight:168.23
IUPAC Name: (E)-3,7-dimethylocta-2,6-dienoic acid
InChIKey: ZHYZQXUYZJNEHD-VQHVLOKHSA-N
SMILES: C/C(C)=C/CC/C(C)=C/C(O)=O
Biological Activity: Geranic acid (Geranate) acts as a tyrosinase inhibitor and antifungal agent, with an IC50 value of 0.14-2.3 mM against mushroom tyrosinase. Geranic acid reduces the viability of human pancreatic cancer cells and B-lymphoma cells. Geranic acid inhibits mycelial growth of the maize pathogens Colletotrichum graminicola and Fusarium graminearum. Geranic acid is applicable to research related to fungal infections, pancreatic cancer and B-lymphoma[1][2][3].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Geranic acid | 90.0% | Geranic acid (Geranate) acts as a tyrosinase inhibitor and antifungal agent, with an IC50 value of 0.14-2.3 mM against mushroom tyrosinase. Geranic acid reduces the viability of human pancreatic cancer cells and B-lymphoma cells. Geranic acid inhibits mycelial growth of the maize pathogens Colletotrichum graminicola and Fusarium graminearum. Geranic acid is applicable to research related to fungal infections, pancreatic cancer and B-lymphoma. | ||||||||||||||||||||
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References
- [1]. Masuda T, et al. Identification of geranic acid, a tyrosinase inhibitor in lemongrass (Cymbopogon citratus). J Agric Food Chem. 2008;56(2):597-601. [Content Brief]
- [2]. Di Mola A, et al. Effect of citral and citral related compounds on viability of pancreatic and human B-lymphoma cell lines[J]. Medicinal Chemistry Research, 2017, 26(3): 631-639.
- [3]. Yang T, et al. Metabolic engineering of geranic acid in maize to achieve fungal resistance is compromised by novel glycosylation patterns. Metab Eng. 2011;13(4):414-425. [Content Brief]
