4725-51-3
Chemical Structure
5α-Androstane-3β,5,6β-triol
- CAS No.: 4725-51-3
- Formula:C19H32O3
- Molecular Weight:308.46
IUPAC Name: (3S,5R,6R,8S,9S,10R,13S,14S)-10,13-dimethylhexadecahydro-5H-cyclopenta[a]phenanthrene-3,5,6-triol
InChIKey: IFRIPYPBJCUNAG-OTMXHXQLSA-N
SMILES: C[C@@]12CCC[C@@]1([H])[C@]3([H])C[C@@H](O)[C@@]4(O)C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC2
Biological Activity: 5α-Androstane-3β,5,6β-triol is a neuroprotectant. 5α-Androstane-3β,5,6β-triol can remarkably reverse intracellular acidification and alleviate neuronal injury through the inhibition of AMPK signaling. 5α-Androstane-3β,5,6β-triol remarkably reduced the infarct volume and attenuated neurologic impairment in acute ischemic stroke models of middle cerebral artery occlusion in vivo[1].
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5α-Androstane-3β,5,6β-triol | 99.74% | 5α-Androstane-3β,5,6β-triol is a neuroprotectant. 5α-Androstane-3β,5,6β-triol can remarkably reverse intracellular acidification and alleviate neuronal injury through the inhibition of AMPK signaling. 5α-Androstane-3β,5,6β-triol remarkably reduced the infarct volume and attenuated neurologic impairment in acute ischemic stroke models of middle cerebral artery occlusion in vivo. | ||||||||||||||||||||
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Keywords
