1. 5α-Androstane-3β,5,6β-triol

5α-Androstane-3β,5,6β-triol is a neuroprotectant. 5α-Androstane-3β,5,6β-triol can remarkably reverse intracellular acidification and alleviate neuronal injury through the inhibition of AMPK signaling. 5α-Androstane-3β,5,6β-triol remarkably reduced the infarct volume and attenuated neurologic impairment in acute ischemic stroke models of middle cerebral artery occlusion in vivo.

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5α-Androstane-3β,5,6β-triol Chemical Structure

5α-Androstane-3β,5,6β-triol Chemical Structure

CAS No. : 4725-51-3

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Description

5α-Androstane-3β,5,6β-triol is a neuroprotectant. 5α-Androstane-3β,5,6β-triol can remarkably reverse intracellular acidification and alleviate neuronal injury through the inhibition of AMPK signaling. 5α-Androstane-3β,5,6β-triol remarkably reduced the infarct volume and attenuated neurologic impairment in acute ischemic stroke models of middle cerebral artery occlusion in vivo[1].

IC50 & Target

AMPK[1]

Molecular Weight

308.46

Formula

C19H32O3

CAS No.
SMILES

C[C@@]12CCC[C@@]1([H])[C@]3([H])C[C@@H](O)[C@@]4(O)C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC2

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5α-Androstane-3β,5,6β-triol
Cat. No.:
HY-100206
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